日韩一级在线播放免费观看-日韩一级特黄-日韩一级视频在线观看播放-日韩一级视频免费观看-俄罗斯a级片-俄罗斯aa毛片一级

服務(wù)熱線

15021010459
產(chǎn)品中心
當(dāng)前位置:主頁(yè) > 產(chǎn)品中心 > > 干細(xì)胞無(wú)血清培養(yǎng)基 >InvivoGen tlrl-pm2s-1 Pam2CSK4 TLR2(6) agonist TLR2(6) 拮抗劑 阻斷劑

InvivoGen tlrl-pm2s-1 Pam2CSK4 TLR2(6) agonist TLR2(6) 拮抗劑 阻斷劑

簡(jiǎn)要描述:TLR2(6) agonist TLR2(6) 拮抗劑,與TLR2(6)蛋白競(jìng)爭(zhēng)性結(jié)合,阻止其他蛋白與他結(jié)合。Pam2CSK4 Synthetic diacylated lipoprotein Pam2CSK4 is a synthetic diacylated lipopeptide (LP).

  • 產(chǎn)品型號(hào):tlrl-pm2s-1
  • 廠商性質(zhì):代理商
  • 更新時(shí)間:2025-02-13
  • 訪  問(wèn)  量:2650
詳細(xì)介紹

TLR2(6) agonist TLR2(6) 拮抗劑,與TLR2(6)蛋白競(jìng)爭(zhēng)性結(jié)合,阻止其他蛋白與他結(jié)合。Pam2CSK4 Synthetic diacylated lipoprotein Pam2CSK4 is a synthetic diacylated lipopeptide (LP).

Pam2CSK4

美國(guó)InvivoGen Invivogen主要提供抗生素,轉(zhuǎn)染試劑,細(xì)胞因子,細(xì)胞系,質(zhì)粒等產(chǎn)品。抗生素涵蓋了細(xì)胞培養(yǎng)、篩選全系列,如Blasticidin S,Hygromycin B, Phleomycin, Primocin,   Zeocin等細(xì)胞分選常用抗生素。尤其以抗細(xì)胞支原體污染的抗生素Plasmocin™zui為出名,該抗生素因其性能受到客戶(hù)*好評(píng)。

Synthetic diacylated lipoprotein
Pam2CSK4 is a synthetic diacylated lipopeptide (LP). According to the current model, diacylated LPs induce signaling through TLR2/6.
However, it was also reported that Pam2CSK4 induces signaling in a TLR6-independent manner. This finding suggests that both the lipid and peptide part of lipoproteins take part in the specificity of recognition by TLR2 heterodimers.
Catalog code change notification

The catalog code of Pam2CSK4 has been changed from "tlrl-pam2" to "tlrl-pm2s" to notify a modification in the production process. Pam2CSK4 "tlrl-pam2" was synthesized in a liquid form, Pam2CSK4 "tlrl-pm2s" is produced by solid-phase peptide synthesis.
Specifications

Specificity: TLR2(6) agonist
Working concentration: 1 - 100 ng/ml
Molecular formula: C65H126N10O12S, 2TFA
Molecular weight: 1271.85
Endotoxin level:  <0.001 EU/μg
Solubility: 1 mg/ml in water
Details


Contents
• Pam2CSK4 is available in two quantities:

- 100 μg: tlrl-pam2
- 1 mg: tlrl-pam2-1

• 1.5 ml sterile endotoxin-free water

Pam2CSK4 is provided as a lyophilized powder and shipped at room temperature. Store at 4°C. Upon resuspension prepare aliquots of Pam2CSK4 and store at 4°C for short term storage or -20°C for long storage. Resuspended product is stable 1 month at 4°C and 6 months at -20°C when properly stored.
Description
Pam2CSK4 is a synthetic diacylated lipopeptide (LP). Bacterial lipoproteins are strong immune modulators that activate early innate host responses after infection. LP analogs of these lipoproteins signal either through TLR2/1 or TLR2/6 heterodimers. According to the current model, triacylated LP like Pam3CSK4, are recognized by TLR2/1, whereas diacylated LP, such as FSL1, induce signaling through TLR2/6. However, it was recently reported that diacylated LP, such as Pam2CSK4, induce signaling in a TLR6-independent manner [1]. This finding suggests that both the lipid and peptide part of lipoproteins take part in the specificity of recognition by TLR2 heterodimers.

1. Buwitt-Beckmann U. et al., 2005. Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur J Immunol. 35(1):282-9.
Citations
Recent articles using Pam2CSK4

 

•2011 - J Immunol., 186: 5916 - 5926
Synergistic interactions of TLR2/6 and TLR9 induce a high level of resistance to lung infection in mice.
 Duggan JM, You D, Cleaver JO, Larson DT, Garza RJ, Guzman Pruneda FA, Tuvim MJ, Zhang J, Dickey BF, Evans SE.
Free article
•2012 - Immunity, 36(3):464-476
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.
 Khare S, Dorfleutner A, Bryan NB, Yun C, Radian AD, de Almeida L, Rojanasakul Y, Stehlik C

•2011 - Clin Vaccine Immunol., 18(11):1834-1844
Assessment of Lactobacillus gasseri as a candidate oral vaccine vector
 Stoeker L, Nordone S, Gunderson S, Zhang L, Kajikawa A, LaVoy A, Miller M, Klaenhammer TR, Dean GA
Free article

 


產(chǎn)品咨詢(xún)

留言框

  • 產(chǎn)品:

  • 您的單位:

  • 您的姓名:

  • 聯(lián)系電話:

  • 常用郵箱:

  • 省份:

  • 詳細(xì)地址:

  • 補(bǔ)充說(shuō)明:

  • 驗(yàn)證碼:

    請(qǐng)輸入計(jì)算結(jié)果(填寫(xiě)阿拉伯?dāng)?shù)字),如:三加四=7
推薦產(chǎn)品

2025 版權(quán)所有 © 重慶市華雅干細(xì)胞技術(shù)有限公司  備案號(hào):渝ICP備14000349號(hào)-4 sitemap.xml 管理登陸 技術(shù)支持:化工儀器網(wǎng)

地址:重慶市江北區(qū)金渝大道153號(hào)8棟20-14 傳真:023-63419626 郵件:sales@ys-bio.com

重慶市華雅干細(xì)胞技術(shù)有限公司主要經(jīng)營(yíng)干細(xì)胞研究 干細(xì)胞治療產(chǎn)品 生物試劑 實(shí)驗(yàn)耗材 藥物研發(fā)等產(chǎn)品。

關(guān)注我們

服務(wù)熱線

400-021-2200

掃一掃,關(guān)注我們

主站蜘蛛池模板: 日本精品视频一视频高清 | 日本肉动漫在线 | 1024手机看片国产旧版你懂的 | 国产99久久久国产精品小说 | 看一级特黄a大片日本片黑人 | 色妞色综合久久夜夜 | 四虎在线网址入口2022 | 在线观看国产精美视频 | 亚洲欧美自拍一区 | 国产国拍亚洲精品福利 | 九月丁香婷婷 | 欧美日韩一区二区在线 | 羞羞视频每日观看 | 请输入搜索词:www免费 | 四虎影视4hutv最新地址在线 | 一级毛片免费不卡直观看 | 禁游app软件下载免费网站 | 日本特黄一级片 | 伊人俺去久久涩五月综合 | 精品国产免费一区二区三区五区 | 欧美成人精品免费播放 | 久久国产精品-久久精品 | 午夜影院入口 | 午夜免费观看_视频在线观看 | 国内精品久久久久久久久久影视 | 欧美视频不卡 | 国产一区二区三区免费观看 | 久久久久女人精品毛片 | 男女做视频网站免费观看 | 久操久热 | 中文字幕无线码一区二区三区 | 亚洲国产精品一区二区三区 | 最新内地三级在线观看 | 国产成人福利免费观看 | 五月婷婷之综合激情 | 久久精品国产99久久久香蕉 | 亚洲免费在线视频播放 | 日本在线高清版卡免v | 亚洲欧美日韩在线精品一区二区 | 亚洲天堂2013 | 久久精品加勒比中文字幕 |